AMA supports requiring obesity education for kids

CHICAGO (AP) ? The American Medical Association on Wednesday put its weight behind requiring yearly instruction aimed at preventing obesity for public schoolchildren and teens.

The nation's largest physicians group agreed to support legislation that would require classes in causes, consequences and prevention of obesity for first through 12th graders. Doctors will be encouraged to volunteer their time to help with that under the new policy adopted on the final day of the AMA's annual policymaking meeting.

Another new policy adopted Wednesday says the AMA supports the idea of taxing sugar-sweetened sodas as one way to help pay for obesity-fighting programs. But the group stopped short of a full-fledged endorsement. Some doctors think soda taxes would disproportionately hurt the poor and disadvantaged. Others said taxes shouldn't be used to force people to make healthful decisions they should be making on their own.

Doctors at the meeting shared sobering statistics and personal stories in urging the AMA to sharpen its focus on obesity prevention.

"I can't tell you the number of 40-pound 1-year-olds I see every day," Dr. Melissa Garretson, a Stephensville, Texas pediatrician, told the delegates before Wednesday's vote. She said requiring obesity education "is a great idea."

The measure was drafted by the AMA's Pennsylvania delegation. It cited data showing that more than 300 million people worldwide are obese and said requiring nutrition education to prevent obesity has never been proposed.

Obesity affects more than one-third of U.S. adults and almost one in five children, or more than 12 million kids. Recent evidence suggests those numbers may have stabilized, but doctors say that's small consolation when so many people are still too fat.

Excess weight is strongly linked with diabetes, heart disease and some cancers, and weight loss of just 5 percent can help improve health, the Pennsylvania doctors' measure said.

Dr. Bruce Wilder, a delegation member, said he will ask Pennsylvania legislators to introduce legislation to enact that requirement in schools.

In other action at the meeting, the AMA voted to:

?urge online social networks to adopt bans on cyber-bullying, or "electronic aggression," on their sites.

?work to reduce suicide among gay, lesbian, bisexual and transgender teens by partnering with public health and policy groups addressing the problem.

?encourage state and local drug courts as an alternative to incarceration for nonviolent criminals.

___

Online: http://www.ama-assn.org

CDC obesity data: http://1.usa.gov/LBuFfb

___

AP Medical Writer Lindsey Tanner can be reached at http://www.twitter.com/LindseyTanner

Associated Press

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Royal Bank of Scotland to cut 600 jobs

The Royal Bank of Scotland is cutting 600 jobs across its branch network, including a number in the north west.

The roles are being cut from its financial planning service in advance of new Financial Services Authority rules which come into force next year, which say that banks must start charging for the previously free service.

The bank said it was cutting the jobs in anticipation of a reduction in demand for the service.

RBS said in a statement: ?The Retail Distribution Review legislation takes effect from December 31, 2012 and will have a fundamental effect on how financial institutions deliver advice to customers across the whole industry, and for the workforce involved.

?From December 31, 2012, customers will be charged a fee for the advice they receive from a qualified professional. If our customers choose financial advice for investment products, the costs will be made transparent at the outset.

?As a response to this, we will be reducing the number of roles by 618 across UK and creating 351 new roles.

?Having to cut jobs is the most difficult part of our work to rebuild RBS and repay taxpayers for their support.?

RBS said it would try to redeploy affected staff and keep compulsory redundancies to a minimum, but union leaders attacked the bank, which is 82 per cent taxpayer owned, for its ?brutal? cuts.

Unite said the cuts represent a 50 per cent reduction in the department across the country.
National officer David Fleming said: "These latest Royal Bank of Scotland job losses are brutal.

?Staff, who for some time have faced job uncertainty as the bank reviewed their jobs, have today heard the worst possible news.

?Unite, for some time, has had major concerns about the appalling manner in which these workers at the bank have been treated.

?The union has continually raised with the bank the increasingly unachievable targets imposed on the workforce and is calling on it to review this redundancy procedure.

?Those losing their jobs today are a highly-skilled workforce, and the bank has refused to take into account economic factors which have impacted performance and achievability of targets.

?Unite will oppose all compulsory job losses and challenge the ongoing management of this area of RBS.?

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Pringle of Scotland's Poignant Finale

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India interest rate unchanged on inflation fears

MUMBAI, India (AP) ? India's central bank left its key interest rate unchanged Monday due to inflation concerns, thwarting hopes of a rate cut to kickstart flagging growth in Asia's third-largest economy.

The Reserve Bank of India said the policy repo rate ? at which it makes short term loans to banks ? would remain unchanged at 8.0 percent, and the cash reserve ratio ? the ratio of cash banks must keep on hand ? would stay at 4.75 percent.

"Future actions will depend on a continuing assessment of external and domestic developments that contribute to lowering inflation risks," the bank said in its policy statement. It said headline inflation remains "above levels consistent with sustainable growth."

Most economists had expected a quarter-point rate cut, given the recent rush of dismal economic data in India and heightened global uncertainty.

India's growth slowed to a nine-year low of 5.3 percent in the quarter ended in March, with the bank blaming weak investment and decelerating industrial output for the slump.

Slowing growth has not tamed inflation. Rising food prices drove India's benchmark inflation rate to 7.6 percent in May from 7.2 percent in April. The steep depreciation of the rupee against the dollar has limited the relief India ? which imports three-quarters of its oil ? had hoped to gain from lower global crude prices.

In April, the Reserve Bank of India surprised markets with a half-percentage-point rate cut, even as it urged New Delhi to tackle supply bottlenecks, reduce the fiscal deficit and improve the investment climate.

"Our assessment of the current growth-inflation dynamic is that there are several factors responsible for the slowdown in activity, particularly in investment, with the role of interest rates being relatively small," the bank said in a statement.

"Consequently, further reduction in the policy interest rate at this juncture, rather than supporting growth, could exacerbate inflationary pressures."

The benchmark Sensex index, which had risen on expectations of a rate cut in early trade, slipped 1.2 percent on the news.

"The Reserve Bank has clearly said that interest rates are not the solution for everything," said Karvy Stock Broking economist Madhavi Arora. New Delhi's surprise decision last week to raise minimum crop prices for Indian farmers will worsen food inflation, she said.

The narrow victory Sunday of a pro-bailout party in Greece reduces the chance of an imminent Greek exit from the eurozone and could stoke a rally in global commodity prices, which would also exacerbate inflation in India, she said.

The bank also took a step to improve credit flow to exporters by raising the cap on banks' export credit refinancing from 15 percent to 50 percent, effective June 30. The Reserve Bank said the move would provide banks in India with 300 billion rupees ($5.4 billion) of additional liquidity.

Associated Press

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Kill the germs, spare the ears: How to create antibiotics that don't hurt hearing

Kill the germs, spare the ears: How to create antibiotics that don't hurt hearing

Tuesday, June 12, 2012

The world needs new antibiotics to overcome the ever increasing resistance of disease-causing bacteria ? but it doesn't need the side effect that comes with some of the most powerful ones now available: hearing loss. Today, researchers report they have developed a new approach to designing antibiotics that kill even "superbugs" but spare the delicate sensory cells of the inner ear.

Surprisingly, they have found that apramycin, an antibiotic already used in veterinary medicine, fits this bill -- setting the stage for testing in humans.

In a paper published online in the Proceedings of the National Academy of Sciences, a team from Switzerland, England and the University of Michigan show apramycin's high efficacy against bacteria, and low potential for causing hearing loss, through a broad range of tests in animals. That testing platform is now being used to evaluate other potential antibiotics that could tackle infections such as multidrug-resistant tuberculosis.

The research aims to overcome a serious limitation of aminoglycoside antibiotics, a class of drugs which includes the widely used kanamycin, gentamicin and amikacin.

While great at stopping bacterial infections, these drugs also cause permanent partial hearing loss in 20 percent of people who take them for a short course, and up to 100 percent of people who take them over months or years, for example to treat tuberculosis or lung infections in cystic fibrosis.

U-M researcher Jochen Schacht, Ph.D., a professor of biological chemistry and otolaryngology and director of the Kresge Hearing Research Institute at the U-M Medical School, has spent decades studying why these drugs cause this "ototoxicity" ? a side effect that makes doctors hesitant to prescribe them. Hearing damage has also caused patients to discontinue treatment before their antibiotic prescription is over, potentially allowing drug-resistant strains of bacteria to flourish.

Schacht has found that the drugs produce damaging free radicals inside the hair cells of the inner ear. Hair cells, named for the tiny sound-sensing hairs on their surface, are the linchpin of hearing ? and once destroyed, cannot be regrown.

In the new paper, Schacht and his research group joined teams led by University of Zurich microbiologist Erik B?ttger, and structural biologist and Nobel Prize winner Venkatraman Ramakrishnan of England's Medical Research Council Laboratory of Molecular Biology, as well as scientists from ETH Zurich. Each team brought its particular expertise to the issue, and after four years of work they developed and tested this new approach to designing antibiotics.

"Aminoglycosides are some of the most valuable broad-spectrum antibiotics and indispensable drugs today, but we need new options to combat drug-resistant bacteria. Importantly, we must find ways to overcome their ototoxicity," Schacht says. "Instead of the trial-and-error approach of the past, this new hypothesis-driven tactic allows us to design drugs with simultaneous attention toward both antibacterial action and impact on hair cells."

According to the World Health Organization, about 440,000 new cases of multidrug-resistant tuberculosis emerge annually, causing at least 150,000 deaths worldwide. Aminoglycoside antibiotics, while carefully controlled in the U.S., Europe, and other developed countries are available over the counter in many developing nations, leading to overuse that makes it even easier for drug-resistant strains of many kinds of bacteria to emerge and spread.

The new paper outlines a rational approach to designing drugs to combat this threat without ototoxicity, based on a theoretical framework that emerged from the work of the three laboratories and centers around the role of ribosomes, the structures inside the cell that ?read? DNA and translate the genetic message into proteins. B?ttger?s lab, at the Institut f?r Medizinische Mikrobiologie which he directs, studies aminoglycoside effects on mitochondrial ribosomes and antibacterial activity with an eye toward designing new ones. Ramakrishnan?s lab studies ribosomes, and partners from ETH Zurich also collaborated.

Aminoglycosides bind to the ribosomes inside bacterial cells, preventing the ability to produce proteins. But while the drugs spare most human ribosomes, they can attach to ribosomes in the mitochondria of cells, which are similar to bacterial ribosomes.

Consistent with U-M-generated theories about ototoxicity, the drugs then cause the production of free radicals in such quantities that they overwhelm the hair cells' defense mechanisms ? destroying the cells and causing hearing loss.

The team's approach is to design drugs that more specifically target bacterial ribosomes over mitochondrial ribosomes, simultaneously testing the impact on hair cells as well as the ability to kill bacteria. In this way, the researchers try to avoid creating antibiotics that harm hearing.

They are already using the platform employed for this study ? which involves cells from mouse ears, and tests of hearing and hair cell damage in guinea pigs ? to test other promising novel drugs synthesized based on the theoretical framework that was driving the current research.

Meanwhile, the team hopes to launch a clinical trial of apramycin, an antibiotic that could prove immediately useful because multidrug-resistant TB and lung-infecting bacteria have not shown resistance to the drug yet.

The research also lends more evidence to support the use of antioxidants to protect the hearing of patients taking current aminoglycoside antibiotics. Schacht has already led a clinical trial in China that showed a major reduction in hearing loss if aspirin was given at the same time as aminoglycoside antibiotics. "This kind of protection is important, while we search for the long-term answer to drug resistance without ototoxicity," he says.

###

University of Michigan Health System: http://www.med.umich.edu

Thanks to University of Michigan Health System for this article.

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Husqvarna 6021P 21-Inch 149cc Kohler XT-6 Gasoline Powered ...

Exceptional Products For Distinctive Yards. Great yards demand tools that's as dedicated and hardworking as you. Fortuitously, the Husqvarna range of garden and garden equipment presents every thing from lawnmowers and journey-on mowers to trimmers and chainsaws to allow you to grasp your great outdoors. You and Husqvarna - together we are going to make your yard the envy of the neighborhood.

The Husqvarna 6021P is an efficient mower featuring a compact design making it simple to maneuver in tight areas, and three reducing programs, assortment, mulch and aspect discharge. Ball-bearing wheels ensure clean operation and durability. The 6021P additionally gives four-point, 9 position reducing top adjustment for various garden conditions. 2 Year Parts & Labor Warranty.

I purchased this mower at my native shop after seeing a significant client rating journal advisable it. Amazon has the photograph improper at the prime of this page. The pic shows a FWD powered mower, and that is NOT a powered mower. Standard old-fashioned push mower. Tremendous straightforward and light-weight to push because of the ball bearings though. I will cut to the chase. First or second pull, starts smoothly and each time. Engine is robust and smooth in every thing but the very tallest of grass. My garden is centipede and cuts very well. Only leaves the occasional straggler which is exceptable to me. Pretty good on gasoline too. My previous Bolens took a tank and half to do my three/4 acre garden, and the Husky does it with only one. (Bone dry though once I finish.)

My only points with this mower is as follows. The froth padding on the handlebars is worthless. After three mows, cracks and falls off. The bagger only works 75 percent of the time. There is a big hole where the underside of the bagger rests and grass falls and blows out. Be prepared to purchase some foam and glue/tape to shut the gap. Where the engine is bolted to the body are also gaps which grass blows out of. I simply duck taped mine up and works tremendous now. In the event you do not maintain the bagger concern and the hole on the deck, be ready to be covered in grass. Also, Kohler components are semi-hard to find. Your gonna have to purchase them off the online or a specialty garden mower shop (no Wally World).

And the spark plug is a Champion 8815 which can also be exhausting to search out instead of the usual RCY ones discovered everywhere. While none of these are deal breakers for me because of the exceptional price and repute of Husqvarna, just be aware of these shortcomings. If they fix the bagger and engine gaps it will be perfect! I'd give Kohler 5 stars for the engine, but I might fee 3.5 to Husky for the deck design.

Straightforward to unbox and put together. Started 2nd pull. Cuts a 1/2 acre lot on one tank of gas. I researched and researched a non-self propelled mower to buy and decided on this model. I learn the evaluations on Kohler engines vs. Briggs and Stratton and thought it was a greater buy. After using this mower I'm not convinced that it's the higher engine (reminds me of an previous Tecumseh engine) and I'd now spring for the Honda engine model7021P over all. My final mower was a self propelled MTD with the Honda engine and that puppy was quiet and had the same slicing power. Ball bearing wheels are nice to push.

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New Mexico, Colorado wildfires burn out of control

LAPORTE, Colo. (AP) ? The sun rose behind a wall of smoke from a large wildfire burning out of control in northern Colorado, while an unchecked blaze choked a small community in southern New Mexico as authorities in both regions on Monday battled fires.

Hundreds of people have evacuated their homes, and dozens of buildings have been destroyed as the fires have spread rapidly, authorities say.

The Colorado fire is burning on nearly 60 square miles in a mountainous area about 15 miles west of Fort Collins. It has grown so fast and put out so much smoke that an evacuee shelter had to be moved. The blaze has damaged or destroyed at least 18 structures.

In New Mexico, a wildfire near the mountain community of Ruidoso has burned more than 40 square miles and damaged or destroyed 35 structures. Some evacuated residents were allowed to return Sunday but were warned to be ready to leave again.

New Mexico Gov. Susana Martinez announced Sunday evening she was ordering 100 National Guard troops mainly to assist with evacuations. They will support the 100 guard members deployed Saturday. They will be dispatched to help at shelters or stationed at various highways where people have to be turned back, Ruidoso spokeswoman Kerry Gladden said.

Military helicopters also have been deployed to drop water at both fires in addition to air tankers dropping slurry.

Smoke from the Colorado fire spread as far away as central Nebraska, western Kansas and Texas.

Strong winds, meanwhile, grounded aircraft at the New Mexico fire on Sunday.

Dan Ware, a spokesman for the New Mexico State Forestry Division, said the number of Ruidoso evacuees was in the hundreds, but he didn?t have an exact figure.

Karen Takai, a spokeswoman for the Ruidoso fire crews, said smoke is heavily affectly the community of Capitan, about five miles to the northeast. She said Capitan and others could also face evacuation.

?Any communities around this fire have the potential of being evacuated,? she said. ?If I lived in Capitan, I definitely would be prepared. Don?t wait until the sheriff?s office comes knocking at your door and tells you to evacuate.?

Both fires were dwarfed by the Whitewater-Baldy blaze in southwest New Mexico ? the largest in the state?s history ? that has charred 450 square miles of wilderness forest since mid-May. But the smaller blazes were especially concerning because they started much closer to more populated areas.

Elsewhere Monday, firefighters were battling a wildfire that blackened six square miles in Wyoming?s Guernsey State Park and forced the evacuation of between 500 and 1,000 campers and visitors.

In Colorado, authorities sent nearly 1,800 evacuation notices to phone numbers, but it wasn?t clear how many residents had to leave. About 500 people had checked in at Red Cross shelters. Larimer County Sheriff Justin Smith said there was an unconfirmed report of a person unaccounted for, but he wouldn?t elaborate.

Authorities say it?s the worst fire seen in Larimer County in about 25 years. It spread as fast as 1? miles an hour Saturday, skipping over some areas but burning intensely in trees in others. Flames were coming dangerously close to deputies who were telling some residents to evacuate, Sheriff Smith said.

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